MCQ Detailed View

The term cVDPV2 stands for circulating vaccine-derived poliovirus type 2. Poliovirus is a highly infectious virus that can cause poliomyelitis, a disease affecting the nervous system and potentially causing paralysis. Poliovirus has three types: type 1, type 2, and type 3.

The “c” in cVDPV2 refers to “circulating,” which means this virus has spread in communities. The “VDPV” stands for “vaccine-derived poliovirus.” These are strains of poliovirus that originate from the oral polio vaccine (OPV), which contains a weakened form of the virus. In rare cases, the weakened virus can mutate during circulation and regain the ability to cause disease, especially in areas with low vaccination coverage. The number 2 specifies the type, which is type II poliovirus.

cVDPV2 is distinct from wild poliovirus, which occurs naturally in the environment. Monitoring and controlling cVDPV2 is critical to polio eradication efforts worldwide. Health organizations, including the World Health Organization (WHO) and UNICEF, conduct vaccination campaigns to prevent outbreaks of cVDPV2 by ensuring high immunization coverage in vulnerable populations.

Understanding cVDPV2 teaches students about virology, vaccine science, public health, and epidemiology. It highlights the importance of immunization programs and how vaccines not only protect individuals but also help prevent the spread of viruses in communities.

This question belongs to Biology, specifically under microbiology, immunology, and public health studies. Knowing the full form and significance of cVDPV2 is essential for understanding modern medical science and disease prevention strategies.